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Osunprotafib

CAT: 0013-GTR19186829-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19186829-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Osunprotafib (ABBV-CLS-484) is an oral PTP1B/PTPN2 inhibitor in clinical development for oncology. It modulates the tumor microenvironment to enhance anti-tumor immunity by potentiating JAK-STAT signaling in NK and CD8+ T cells, thereby reducing T cell exhaustion, as evidenced in preclinical in vivo studies.
CAS Number
2489404-97-7
Product Name Alternative
Osunprotafib, AC 484, AC 484, ABBV-CLS 484, ABBV-CLS484, ABBV-CLS-484, AC484, AC-484, protein tyrosine phosphatase (PTP)
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Metabolism Research, Signal Transduction, Stem Cell & Developmental Biology
Purity
97.11% (May vary between batches)
Form
Powder
Solubility
DMSO: 56.2 mg/mL (145.9 mM), Sonication is recommended. H2O: < 1 mg/mL (insoluble)
Smiles
CC (C) CCN[C@@H]1CCc2cc (O) c (N3CC (=O) NS3 (=O) =O) c (F) c2C1
Molecular Formula
C17H24FN3O4S
Molecular Weight
385.45
Storage Conditions
Powder: -20°C
Notes
For research use only.

Alternative Products

CatalogName
M35583-01Osunprotafib
T211442-01Osunprotafib hydrochloride
HY-145923BOsunprotafib (hydrochloride)
C01543-1mgOsunprotafib (ABBV-CLS-484)

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