Products for Research Use Only
RegisterLogin

AZD7254

CAT: 0013-GTR19186625-03Size: 100 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19186625-03Size:100 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
AZD7254 is a potent and orally bioavailable Smoothened (SMO) antagonist with an EC50 of 1.0 nM against Sonic Hedgehog (Shh) signaling. This inhibitor is a valuable research tool for investigating the Hedgehog pathway in both cellular assays and in vivo models of related cancers and disorders.
CAS Number
1126366-28-6
Field of Research
Stem Cell & Developmental Biology
Smiles
CC=1C (=CC (NC (=O) C2=CC=C (OCC3=CC=CC=N3) C=C2) =C (C) C1) C=4NC=CN4
Molecular Formula
C24H22N4O2
Molecular Weight
398.46
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

N-[5-(1H-Imidazol-2-yl)-2,4-dimethylphenyl]-4-(pyridin-2-ylmethoxy)benzamide
CAS Number1126366-28-6
PubChem CID25253713
IUPAC NameN-[5-(1H-imidazol-2-yl)-2,4-dimethylphenyl]-4-(pyridin-2-ylmethoxy)benzamide
Molecular FormulaC24H22N4O2
Molecular Weight398.5
XLogP3.7
Topological Polar Surface Area79.9
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count6
Heavy Atom Count30
Formal Charge0
Complexity551
SMILES
CC1=CC(=C(C=C1C2=NC=CN2)NC(=O)C3=CC=C(C=C3)OCC4=CC=CC=N4)C
InChI
InChI=1S/C24H22N4O2/c1-16-13-17(2)22(14-21(16)23-26-11-12-27-23)28-24(29)18-6-8-20(9-7-18)30-15-19-5-3-4-10-25-19/h3-14H,15H2,1-2H3,(H,26,27)(H,28,29)
InChIKey
BEZRNHWRVKFZJX-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of N-[5-(1H-Imidazol-2-yl)-2,4-dimethylphenyl]-4-(pyridin-2-ylmethoxy)benzamide
CAS: 1126366-28-6
CID: 25253713
Formula: C24H22N4O2
MW: 398.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight398.5
XLogP33.7
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count6
Exact Mass398.17427596
Monoisotopic Mass398.17427596
Topological Polar Surface Area79.9 Ų
Heavy Atom Count30
Formal Charge0
Complexity551
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19213328AZD8154
GTR19174859-01AZD7545
GTR19160381-01AZD7545
GTR19175184-01AZD7624
GTR19209189-01AZD7451
GTR19198165-01AZD7268
GTR19168096-01AZD3264
GTR19167471-01AZD7325
GTR19162987-01AZD3264

Alternative Products

CatalogName
T61895-01AZD7254

Popular Products