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KRAS inhibitor-12

CAT: 0013-GTR19185836-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19185836-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
KRAS inhibitor-12 is a potent and selective KRAS G12C inhibitor with an IC50 of 0.537 μM. It effectively suppresses p-ERK signaling in cellular models such as MIA PaCa-2 and A549 cells, supporting its research utility in pancreatic, colorectal, and non-small cell lung cancer studies.
CAS Number
2230874-00-5
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Smiles
FC=1C=2C (=C (SN2) N3CCN (C (C=C) =O) CC3) C=C (Cl) C1C4=C (Cl) C=CC (N) =N4
Molecular Formula
C19H16Cl2FN5OS
Molecular Weight
452.33
Storage Conditions
-20°C
Notes
For research use only.

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