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CDK6/PIM1-IN-1

CAT: 0013-GTR19185957-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19185957-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CDK6/PIM1-IN-1 is a potent dual inhibitor of CDK6 (IC50: 39 nM) and PIM1 (IC50: 88 nM), also strongly inhibiting CDK4 (IC50: 3.6 nM) . It demonstrates anti-AML activity by inhibiting cell proliferation, inducing G1 phase arrest, and promoting apoptosis in acute myeloid leukemia models.
CAS Number
2677026-14-9
Field of Research
Cell Biology, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Smiles
N (CC) (CC) C1=NC2=C (C=CC (=C2) C3=NC (NC4=CC=C (C=N4) N5CCNCC5) =NC=C3F) N=C1
Molecular Formula
C25H28FN9
Molecular Weight
473.55
Storage Conditions
-20°C
Notes
For research use only.

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HY-142696CDK6/PIM1-IN-1
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