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KRAS inhibitor-14

CAT: 0013-GTR19185425-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19185425-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
KRAS inhibitor-14 is a potent and selective KRAS G12C inhibitor with an IC50 of 0.249 μM. It demonstrates functional activity by inhibiting p-ERK in cellular assays, such as in MIA PaCA-2 cells, supporting its research application in pancreatic, colorectal, and non-small cell lung cancer models.
CAS Number
2230873-78-4
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Smiles
FC=1C=2C (=C (SN2) N3CCN (C (C=C) =O) CC3) C=C (Cl) C1C4=C (Cl) C (Cl) =CC (O) =C4
Molecular Formula
C20H15Cl3FN3O2S
Molecular Weight
486.77
Storage Conditions
-20°C
Notes
For research use only.

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