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PF-8380 hydrochloride

CAT: 0013-GTR19185066Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19185066Size:500 mg
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Description
PF-8380 hydrochloride is a potent and selective autotaxin inhibitor with an IC50 of 2.8 nM in enzymatic assays and 101 nM in human whole blood. This tool compound is widely used in preclinical research to investigate lysophosphatidic acid (LPA) signaling in fibrosis, cancer, and neuropathic pain models, both in vitro and in vivo.
CAS Number
2070015-01-7
Field of Research
Metabolism Research
Smiles
Cl.Clc1cc (Cl) cc (COC (=O) N2CCN (CCC (=O) c3ccc4[nH]c (=O) oc4c3) CC2) c1
Molecular Formula
C22H22Cl3N3O5
Molecular Weight
514.79
Storage Conditions
-20°C
Notes
For research use only.

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