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ATX inhibitor 12

CAT: 0013-GTR19185056-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19185056-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ATX inhibitor 12 is a potent, orally bioavailable small molecule inhibitor of autotaxin, exhibiting an IC50 of 1.72 nM. In vivo studies in a C57Bl/6J mouse model demonstrated that oral dosing at 60 mg/kg effectively attenuated structural lung damage and fibrosis, supporting its research use in fibrotic disease investigations.
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Molecular Formula
C30H34FN5O2
Molecular Weight
515.62
Storage Conditions
-20°C
Notes
For research use only.

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