Physalin B

CAT: 0013-GTR19183222-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19183222-01Size:1 mg

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Description

Physalin B, a bioactive compound from Solanaceae plants, exhibits broad anti-inflammatory and antitumor activities. It attenuates acute lung injury by suppressing NF-κB/NLRP3 via PI3K/Akt and inhibits VSMC proliferation via the Nrf2 pathway. Research applications include studies in inflammation, vascular remodeling, and oncology using in vitro and in vivo models.

CAS Number

23133-56-4

Product Name Alternative

Akt, Antifection, Apoptosis, Bcl-2, Caspase, NSC287088, NSC-287088, NOD, NFkB, NF-kB, NFκB, NF-κB, NSC 287088, Nrf2, PI3K, Physalin B

Field of Research

Cell Biology, Immunology & Inflammation, Signal Transduction

Purity

97.20% (May vary between batches)

Smiles

[H][C@@]12C (=O) [C@]34O[C@]11[C@@] (C) (OC (=O) [C@@]1 (O) CC[C@@]1 ([H]) [C@@]3 ([H]) CC=C3CC=CC (=O) [C@]13C) [C@H]1C[C@]2 (C) [C@@] ([H]) (CO4) C (=O) O1

Molecular Formula

C28H30O9

Molecular Weight

510.53

Storage Conditions

Store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Notes

For research use only.

Chemical Information

Physalin B

CID 11613161 has been reported in Witheringia solanacea, Alkekengi officinarum, and other organisms with data available.

CAS Number	23133-56-4
PubChem CID	11613161
IUPAC Name	(1R,2S,5R,8S,9R,17R,18R,21S,24R,26S,27S)-5-hydroxy-2,9,26-trimethyl-3,19,23,28-tetraoxaoctacyclo[16.9.1.118,27.01,5.02,24.08,17.09,14.021,26]nonacosa-11,14-diene-4,10,22,29-tetrone
Molecular Formula	C28H30O9
Molecular Weight	510.5
XLogP	0.8
Topological Polar Surface Area	125
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	9
Rotatable Bond Count	0
Heavy Atom Count	37
Formal Charge	0
Complexity	1300

SMILES

C[C@]12C[C@@H]3[C@]4([C@]56[C@H]1C(=O)[C@](O5)([C@@H]7CC=C8CC=CC(=O)[C@@]8([C@H]7CC[C@@]6(C(=O)O4)O)C)OC[C@H]2C(=O)O3)C

InChI

InChI=1S/C28H30O9/c1-23-11-18-25(3)28-19(23)20(30)27(37-28,34-12-16(23)21(31)35-18)15-8-7-13-5-4-6-17(29)24(13,2)14(15)9-10-26(28,33)22(32)36-25/h4,6-7,14-16,18-19,33H,5,8-12H2,1-3H3/t14-,15+,16-,18+,19-,23+,24-,25-,26-,27+,28-/m0/s1

InChIKey

HVTFEHJSUSPQBK-DNJDGUCCSA-N

Chemical Structure

2D Structure

CAS: 23133-56-4

CID: 11613161

Formula: C28H30O9

MW: 510.5

Interactive 3D Structure

Loading 3D structure...

View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	510.5
XLogP3	0.8
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	9
Rotatable Bond Count	0
Exact Mass	510.18898253
Monoisotopic Mass	510.18898253
Topological Polar Surface Area	125 Å²
Heavy Atom Count	37
Formal Charge	0
Complexity	1300
Isotope Atom Count	0
Defined Atom Stereocenter Count	11
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Related Products

Catalog	Name
GTR19180818-01	Physalin A
GTR19217243-01	Physalin L
GTR19269491	Physalin C
GTR19221895-01	Physalin C
GTR19180814-01	Physalin O
GTR19180817	Physalin D
GTR19165925-01	Physalin F
GTR19233295	Physalin X
GTR19183684-01	Physalin L
GTR19260231-01	Physalin C

Alternative Products

Catalog	Name
TRC-P397900-1MG	Physalin A
VEA84918-01	Physalin O
TN4776	Physalin D
583133	Physalin F
MBS3612675-01	Physalin L
MBS5786776	Physalin B
MBS5762941	Physalin G
TN7372-01	Physalin X

Physalin B

Chemical Information

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