Products for Research Use Only
RegisterLogin

Pelecopan

CAT: 0013-GTR19186991-01Size: 25 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19186991-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Pelecopan (BCX9930) is an orally bioavailable, potent, and selective inhibitor of complement factor D with an IC50 of 14.3 nM. It is a research tool for studying the alternative complement pathway in PNH models, demonstrating efficacy in preventing both intravascular and extravascular hemolysis in preclinical studies.
CAS Number
2378380-49-3
Field of Research
Immunology & Inflammation
Smiles
FC=1C (C2=C3C (=CC (COC4=C (CC (O) =O) C=CC=C4) =C2) C=CO3) =CC=NC1CN
Molecular Formula
C23H19FN2O4
Molecular Weight
406.41
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Pelecopan

Pelecopan is a small molecule drug. The usage of the INN stem '-copan' in the name indicates that Pelecopan is a complement receptor antagonist/complement inhibitor. Pelecopan has a monoisotopic molecular weight of 406.13 Da.

CAS Number2378380-49-3
PubChem CID139560984
IUPAC Name2-[2-[[7-[2-(aminomethyl)-3-fluoro-4-pyridinyl]-1-benzofuran-5-yl]methoxy]phenyl]acetic acid
Molecular FormulaC23H19FN2O4
Molecular Weight406.4
XLogP0.5
Topological Polar Surface Area98.6
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count7
Rotatable Bond Count7
Heavy Atom Count30
Formal Charge0
Complexity579
SMILES
C1=CC=C(C(=C1)CC(=O)O)OCC2=CC(=C3C(=C2)C=CO3)C4=C(C(=NC=C4)CN)F
InChI
InChI=1S/C23H19FN2O4/c24-22-17(5-7-26-19(22)12-25)18-10-14(9-16-6-8-29-23(16)18)13-30-20-4-2-1-3-15(20)11-21(27)28/h1-10H,11-13,25H2,(H,27,28)
InChIKey
AUARNXJEAZFQCQ-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Pelecopan
CAS: 2378380-49-3
CID: 139560984
Formula: C23H19FN2O4
MW: 406.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight406.4
XLogP30.5
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count7
Rotatable Bond Count7
Exact Mass406.13288525
Monoisotopic Mass406.13288525
Topological Polar Surface Area98.6 Ų
Heavy Atom Count30
Formal Charge0
Complexity579
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
T62020-01Pelecopan
A24473-50Pelecopan (BCX9930) 50mg
A24473-10Pelecopan (BCX9930) 10mg
A24473-5Pelecopan (BCX9930) 5mg
A24473-100Pelecopan (BCX9930) 100mg

Popular Products