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EGFR-IN-55

CAT: 0013-GTR19184936-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19184936-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
EGFR-IN-55 is a potent small molecule inhibitor targeting both wild-type EGFR (IC50 = 70 nM) and the resistant EGFRL858R/T790M mutant (IC50 = 3.9 nM) . It demonstrates anticancer activity by inducing G0/G1 phase cell cycle arrest in NCI-H1975 cells, making it a valuable tool for in vitro research in non-small cell lung cancer and kinase signaling pathways.
CAS Number
2057423-46-6
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
N (C1=CC=C (C=C1) N2CCN (C (C) =O) CC2) C=3N=C (NC4=CC (NC (C (=C) Cl) =O) =CC=C4) C (Cl) =CN3
Molecular Formula
C25H25Cl2N7O2
Molecular Weight
526.42
Storage Conditions
-20°C
Notes
For research use only.

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