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Pomalidomide-PEG4-C2-NH2

CAT: 0013-GTR19178098-02Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19178098-02Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This conjugate features a pomalidomide-based cereblon ligand linked via a tetraethylene glycol (PEG4) spacer. It serves as a key component in the construction of PROTACs and other bifunctional molecules for targeted protein degradation research, applicable in both cellular and in vivo experimental models.
CAS Number
2225940-52-1
Product Name Alternative
Inhibit, Ligand for E3 Ligase, LigandforE3Ligase, Inhibitor, E3 Ligase Ligand-Linker Conjugates 22, E3 Ligase Ligand-Linker Conjugates, Cereblon, Cereblon Ligand-Linker Conjugates 8, PomalidomidePEG4C2NH2, Pomalidomide-PEG4-C2-NH2, Pomalidomide PEG4 C2 NH2
Field of Research
Pharmacology & Drug Discovery
Purity
95.73% (May vary between batches)
Solubility
DMSO:45 mg/mL (91.37 mM)
Smiles
O=C1C=2C (C (=O) N1C3C (=O) NC (=O) CC3) =CC=CC2NCCOCCOCCOCCOCCN
Molecular Formula
C23H32N4O8
Molecular Weight
492.52
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Pomalidomide-PEG4-C2-NH2
CAS Number2225940-52-1
PubChem CID134821686
IUPAC Name4-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethylamino]-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione
Molecular FormulaC23H32N4O8
Molecular Weight492.5
XLogP-0.7
Topological Polar Surface Area159
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count10
Rotatable Bond Count16
Heavy Atom Count35
Formal Charge0
Complexity736
SMILES
C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)NCCOCCOCCOCCOCCN
InChI
InChI=1S/C23H32N4O8/c24-6-8-32-10-12-34-14-15-35-13-11-33-9-7-25-17-3-1-2-16-20(17)23(31)27(22(16)30)18-4-5-19(28)26-21(18)29/h1-3,18,25H,4-15,24H2,(H,26,28,29)
InChIKey
RMLHAPHCRDKBTD-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Pomalidomide-PEG4-C2-NH2
CAS: 2225940-52-1
CID: 134821686
Formula: C23H32N4O8
MW: 492.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight492.5
XLogP3-0.7
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count10
Rotatable Bond Count16
Exact Mass492.22201399
Monoisotopic Mass492.22201399
Topological Polar Surface Area159 Ų
Heavy Atom Count35
Formal Charge0
Complexity736
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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Alternative Products

CatalogName
HY-112599-01Pomalidomide-PEG4-C2-NH2
A20076-1000Pomalidomide-PEG4-C2-NH2 1g
A20076-500Pomalidomide-PEG4-C2-NH2 500mg
A20076-25Pomalidomide-PEG4-C2-NH2 25mg
BUP11385-01Pomalidomide-PEG4-C2-NH2 hydrochloride
HY-112599B-01Pomalidomide-PEG4-C2-NH2 (hydrochloride)
A20076-2000Pomalidomide-PEG4-C2-NH2 2g
A20076-5Pomalidomide-PEG4-C2-NH2 5mg
A20076-2Pomalidomide-PEG4-C2-NH2 2mg
A20076-100Pomalidomide-PEG4-C2-NH2 100mg

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