Products for Research Use Only

Cbz-NH-PEG5-CH2COOH

CAT: 0013-GTR19177703Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19177703Size:50 mg
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Description
Cbz-NH-PEG5-CH2COOH is a heterobifunctional PROTAC linker featuring a carbobenzyloxy-protected amine and a terminal carboxylic acid, connected by a flexible pentafethylene glycol) spacer. This water-soluble linker is widely used in chemical biology for constructing proteolysis-targeting chimeras (PROTACs) for both in vitro and in vivo degradation studies.
CAS Number
1449390-66-2
Product Name Alternative
PEGs, PROTAC Linkers, PROTAC Linker, PROTACLinker, inhibit, Inhibitor, Cbz NH PEG5 CH2COOH, CbzNHPEG5CH2COOH, Cbz-NH-PEG-5-CH2COOH, Cbz-NH-PEG5-CH2COOH
Field of Research
Pharmacology & Drug Discovery, Stem Cell & Developmental Biology
Purity
98.33% (May vary between batches)
Smiles
C (OC (NCCOCCOCCOCCOCCOCC (O) =O) =O) C1=CC=CC=C1
Molecular Formula
C20H31NO9
Molecular Weight
429.46
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Cbz-NH-peg5-CH2cooh
CAS Number1449390-66-2
PubChem CID118986708
IUPAC Name2-[2-[2-[2-[2-[2-(phenylmethoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]acetic acid
Molecular FormulaC20H31NO9
Molecular Weight429.5
XLogP0.3
Topological Polar Surface Area122
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count9
Rotatable Bond Count20
Heavy Atom Count30
Formal Charge0
Complexity431
SMILES
C1=CC=C(C=C1)COC(=O)NCCOCCOCCOCCOCCOCC(=O)O
InChI
InChI=1S/C20H31NO9/c22-19(23)17-29-15-14-28-13-12-27-11-10-26-9-8-25-7-6-21-20(24)30-16-18-4-2-1-3-5-18/h1-5H,6-17H2,(H,21,24)(H,22,23)
InChIKey
JEVLWNSJFGPKCP-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Cbz-NH-peg5-CH2cooh
CAS: 1449390-66-2
CID: 118986708
Formula: C20H31NO9
MW: 429.5
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight429.5
XLogP30.3
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count9
Rotatable Bond Count20
Exact Mass429.19988157
Monoisotopic Mass429.19988157
Topological Polar Surface Area122 Ų
Heavy Atom Count30
Formal Charge0
Complexity431
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes