Products for Research Use Only

Cbz-NH-PEG2-CH2COOH

CAT: 0013-GTR19216792-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19216792-01Size:200 mg
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Description
Cbz-NH-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. (In Vitro) :PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
CAS Number
165454-06-8
Field of Research
Metabolism Research
Purity
>98% (HPLC)
Smiles
OC (=O) COCCOCCNC (=O) OCc1ccccc1
Molecular Formula
C14H19NO6
Molecular Weight
297.307
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

Chemical Information

3-Oxo-1-phenyl-2,7,10-trioxa-4-azadodecan-12-oic acid
CAS Number165454-06-8
PubChem CID10935367
IUPAC Name2-[2-[2-(phenylmethoxycarbonylamino)ethoxy]ethoxy]acetic acid
Molecular FormulaC14H19NO6
Molecular Weight297.30
XLogP0.7
Topological Polar Surface Area94.1
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count11
Heavy Atom Count21
Formal Charge0
Complexity304
SMILES
C1=CC=C(C=C1)COC(=O)NCCOCCOCC(=O)O
InChI
InChI=1S/C14H19NO6/c16-13(17)11-20-9-8-19-7-6-15-14(18)21-10-12-4-2-1-3-5-12/h1-5H,6-11H2,(H,15,18)(H,16,17)
InChIKey
GWUWSVXMAZFFNT-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 3-Oxo-1-phenyl-2,7,10-trioxa-4-azadodecan-12-oic acid
CAS: 165454-06-8
CID: 10935367
Formula: C14H19NO6
MW: 297.30
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight297.30
XLogP30.7
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count11
Exact Mass297.12123733
Monoisotopic Mass297.12123733
Topological Polar Surface Area94.1 Ų
Heavy Atom Count21
Formal Charge0
Complexity304
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes