Products for Research Use Only
RegisterLogin

BPH-1358

CAT: 0013-GTR19178179-05Size: 50 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19178179-05Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
BPH-1358 (NSC-50460) is a dual inhibitor of human FPPS and bacterial UPPS with IC50 values of 1.8 μM and 110 nM, respectively. It exhibits in vitro antibacterial activity against S. aureus (MIC ~250 ng/mL) and serves as a research tool for studying isoprenoid biosynthesis and antimicrobial strategies.
CAS Number
5352-53-4
Product Name Alternative
Bacterial, BPH 1358, BPH1358, BPH-1358, inhibit, Inhibitor, NSC 50460, NSC50460, NSC-50460, FPPS, human bisphosphonate farnesyl diphosphate synthase
Field of Research
Infectious Disease & Virology
Purity
99.63% (May vary between batches)
Solubility
DMSO:Slightly soluble
Smiles
O=C (C1=CC=C (C2=CC=C (C (NC3=CC=CC (C4=NCCN4) =C3) =O) C=C2) C=C1) NC5=CC=CC (C6=NCCN6) =C5.[H]Cl.[H]Cl
Molecular Formula
C32H30Cl2N6O2
Molecular Weight
601.53
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

N-[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]-4-[4-[[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]carbamoyl]phenyl]benzamide;dihydrochloride
CAS Number5352-53-4
PubChem CID139600276
IUPAC NameN-[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]-4-[4-[[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]carbamoyl]phenyl]benzamide;dihydrochloride
Molecular FormulaC32H30Cl2N6O2
Molecular Weight601.5
Topological Polar Surface Area107
Hydrogen Bond Donor Count6
Hydrogen Bond Acceptor Count4
Rotatable Bond Count7
Heavy Atom Count42
Formal Charge0
Complexity873
SMILES
C1CN=C(N1)C2=CC(=CC=C2)NC(=O)C3=CC=C(C=C3)C4=CC=C(C=C4)C(=O)NC5=CC=CC(=C5)C6=NCCN6.Cl.Cl
InChI
InChI=1S/C32H28N6O2.2ClH/c39-31(37-27-5-1-3-25(19-27)29-33-15-16-34-29)23-11-7-21(8-12-23)22-9-13-24(14-10-22)32(40)38-28-6-2-4-26(20-28)30-35-17-18-36-30;;/h1-14,19-20H,15-18H2,(H,33,34)(H,35,36)(H,37,39)(H,38,40);2*1H
InChIKey
ASVCJNSPDDRTOQ-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of N-[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]-4-[4-[[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]carbamoyl]phenyl]benzamide;dihydrochloride
CAS: 5352-53-4
CID: 139600276
Formula: C32H30Cl2N6O2
MW: 601.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight601.5
Hydrogen Bond Donor Count6
Hydrogen Bond Acceptor Count4
Rotatable Bond Count7
Exact Mass600.1807296
Monoisotopic Mass600.1807296
Topological Polar Surface Area107 Ų
Heavy Atom Count42
Formal Charge0
Complexity873
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count3
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19206399-01BPH-652
GTR19200532-01BPH-651
GTR19175100-01BPH-715
GTR19200533-01BPH-1218
GTR19188177-01BPH-1086
GTR19172668-01CNX-1351
GTR19195840-01AH 135Y
GTR19172216-01PF-1355
GTR19160769-01CNX-1351
GTR19209508-01H-1356

Alternative Products

CatalogName
T10586L-01BPH-1358
HY-118946BBPH-1358 (mesylate)
MBS5814925BPH-1358 mesylate
HY-118946ABPH-1358 (free base)
T10586-01BPH-1358 free base
PH2006015-01PathoScope 1358 Panel
BA2136-10BPH-715
HY-113869BPH-628
T30570-01BPH-830
T30567-01BPH-675

Popular Products