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BRD5648

CAT: 0013-GTR19178079-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19178079-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BRD0705 is a paracrine-selective, orally bioavailable GSK3α inhibitor with a Kd of 4.8 μM and an IC50 of 66 nM, exhibiting 8-fold selectivity over GSK3β. It serves as a research tool for studying acute myeloid leukemia, with applications in both in vitro and in vivo experimental models. BRD5648 functions as its corresponding negative control compound.
CAS Number
2056261-42-6
Product Name Alternative
Compound, BRD0705, BRD-0705, BRD 5648, BRD 0705, BRD5648, BRD-5648, control, (R) -enantiomer, (R) -BRD0705, Inhibitor, Glycogen synthase kinase 3, Glycogen synthase kinase-3, GSK3, GSK-3, GSK-3α, inhibit, negative
Field of Research
Signal Transduction, Stem Cell & Developmental Biology
Purity
99.37% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (15.56 mM) ; DMSO:300 mg/mL (933.36 mM)
Smiles
CC[C@]1 (C2=CNNC2=NC2=C1C (=O) CC (C) (C) C2) c1ccccc1
Molecular Formula
C20H23N3O
Molecular Weight
321.42
Storage Conditions
-20°C
Notes
For research use only.

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