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LSP-249

CAT: 0013-GTR19176700-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19176700-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LSP-249 is a potent small molecule inhibitor of plasma kallikrein, exhibiting an EC50 below 100 nM in cellular assays. It is a valuable research tool for investigating hereditary angioedema (HAE) pathophysiology and for preclinical in vitro and in vivo studies targeting kallikrein-mediated pathways.
CAS Number
1801253-04-2
Product Name Alternative
Angioedema, LSP 249, LSP249, LSP-249, Inhibitor, kallikrein, kallikrein in cell, inhibit, Threonine proteases, Serine proteases, Ser/Thr Protease, Serine endopeptidases
Field of Research
Protein Biochemistry
Purity
99.27% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.63 mM) ; DMSO:31.25 mg/mL (72.35 mM)
Smiles
Cc1cc (N) nc (C) c1CNC (=O) c1ccnc (Cc2ccc3ncc (Cl) cc3c2) c1
Molecular Formula
C24H22ClN5O
Molecular Weight
431.92
Storage Conditions
-20°C
Notes
For research use only.

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