PF-04802367

• Target :

  GSK-3

• Related Pathways :

  Stem Cells|||PI3K/Akt/mTOR signaling

• Purity :

  0.9876

• Bioactivity :

  PF-04802367 is a highly selective GSK-3 inhibitor with an IC50 of 2.1 nM based on a recombinant human GSK-3? enzyme assay and 1.1 nM based on ADP-Glo assay. It shows desirable central nervous system (CNS) properties and potency. It is equally effective at inhibition of the two known GSK-3 isoforms (GSK-3? and GSK-3?) with IC50 values of 10.0 and 9.0 nM in mobility shift assays, respectively.

• Smiles :

  COc1ccc(cc1Cl)-c1ocnc1C(=O)NCCCn1cncn1

• Molecular Formula :

  C16H16ClN5O3

• Molecular Weight :

  361.78

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1962178-27-3