Products for Research Use Only

Talmapimod

CAT: 0013-GTR19175811-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19175811-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Talmapimod (SCIO-469) is a potent, orally bioavailable, and highly selective ATP-competitive inhibitor of p38α MAP kinase (IC50 = 9 nM) . It demonstrates significant selectivity over p38β and other kinases. This compound has been utilized in research to investigate p38α's role in inflammatory pathways in both cellular and animal models.
CAS Number
309913-83-5
Product Name Alternative
Cells, cytotoxicity, Hsp27, Inhibitor, inhibit, myeloma, multiple, p38 MAPK, p38α, p38β, p38MAPK, phosphorylation, Talmapimod, SCIO 469, SCIO469, SCIO-469, tumor
Field of Research
Signal Transduction
Purity
98.00% (May vary between batches)
Solubility
DMSO:95 mg/mL (185.19 mM)
Smiles
C[C@H]1CN ([C@H] (C) CN1Cc1ccc (F) cc1) C (=O) c1cc2c (cn (C) c2cc1Cl) C (=O) C (=O) N (C) C
Molecular Formula
C27H30ClFN4O3
Molecular Weight
513
Storage Conditions
-20°C
Notes
For research use only.