Talmapimod hydrochloride

• Target:

  P38 MAPK

• Related Pathways:

  MAPK

• Bioactivity:

  Talmapimod hydrochloride is a selective and ATP-competitive p38? inhibitor (IC50: 9 nM) . It also shows about 10-fold selectivity over p38?, and at least 2000-fold selectivity over a panel of 20 other kinases, including other MAPKs.

• Smiles:

  Cl.C[C@H]1CN ([C@H] (C) CN1Cc1ccc (F) cc1) C (=O) c1cc2c (cn (C) c2cc1Cl) C (=O) C (=O) N (C) C

• Molecular Formula:

  C27H31Cl2FN4O3

• Molecular Weight:

  549.46

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  309915-12-6