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Talmapimod hydrochloride

CAT: 0931-T12871L-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0931-T12871L-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
309915-12-6
Target
P38 MAPK
Related Pathways
MAPK
Bioactivity
Talmapimod hydrochloride is a selective and ATP-competitive p38α inhibitor (IC50: 9 nM) . It also shows about 10-fold selectivity over p38β, and at least 2000-fold selectivity over a panel of 20 other kinases, including other MAPKs.
Smiles
Cl.C[C@H]1CN([C@H](C)CN1Cc1ccc(F)cc1)C(=O)c1cc2c(cn(C)c2cc1Cl)C(=O)C(=O)N(C)C
Molecular Formula
C27H31Cl2FN4O3
Molecular Weight
549.46
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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