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Talmapimod

CAT: 0931-T12871-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T12871-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
309913-83-5
Target
P38 MAPK
Related Pathways
MAPK
Purity
>99.99%
Bioactivity
Talmapimod (SCIO-469) is a selective, orally active, ATP-competitive p38α inhibitor with IC50 values of 9 nM for p38α and 90 nM for p38β. Talmapimod exhibits at least 2000-fold selectivity over a panel of 20 kinases, including other MAPKs.
Smiles
C[C@H]1CN([C@H](C)CN1Cc1ccc(F)cc1)C(=O)c1cc2c(cn(C)c2cc1Cl)C(=O)C(=O)N(C)C
Molecular Formula
C27H30ClFN4O3
Molecular Weight
513
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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