ICAM-1-IN-1

CAT: 0013-GTR19175704-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19175704-01Size:1 mg

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Description

ICAM-1-IN-1 is a potent dual inhibitor of E-selectin (IC50 = 7 nM) and ICAM-1 (IC50 = 5 nM) . This small molecule is a valuable research tool for studying cell adhesion and inflammation in vitro and has shown efficacy in animal models of inflammatory diseases.

CAS Number

251994-14-6

Product Name Alternative

ICAM 1 IN 1, ICAM-1, ICAM1IN1, ICAM-1-IN-1, E-selectin, Inhibitor, Integrin, inhibit

Field of Research

Immunology & Inflammation, Signal Transduction

Purity

99.34% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.51 mM) ; DMSO:50 mg/mL (137.65 mM)

Smiles

CNC (=O) c1cc2c (Oc3ccc (Br) cc3) cncc2s1

Molecular Formula

C15H11BrN2O2S

Molecular Weight

363.23

Storage Conditions

-20°C

Notes

For research use only.

Chemical Information

Cam-IN-1

CAS Number	251994-14-6
PubChem CID	10361323
IUPAC Name	4-(4-bromophenoxy)-N-methylthieno[2,3-c]pyridine-2-carboxamide
Molecular Formula	C15H11BrN2O2S
Molecular Weight	363.2
XLogP	3.7
Topological Polar Surface Area	79.5
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	3
Heavy Atom Count	21
Formal Charge	0
Complexity	377

SMILES

CNC(=O)C1=CC2=C(S1)C=NC=C2OC3=CC=C(C=C3)Br

InChI

InChI=1S/C15H11BrN2O2S/c1-17-15(19)13-6-11-12(7-18-8-14(11)21-13)20-10-4-2-9(16)3-5-10/h2-8H,1H3,(H,17,19)

InChIKey

OFXAEWYLVPBGGU-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 251994-14-6

CID: 10361323

Formula: C15H11BrN2O2S

MW: 363.2

Interactive 3D Structure

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View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	363.2
XLogP3	3.7
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	3
Exact Mass	361.97246
Monoisotopic Mass	361.97246
Topological Polar Surface Area	79.5 Å²
Heavy Atom Count	21
Formal Charge	0
Complexity	377
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

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GTR18039839-01	ICAM-1 polyclonal antibody

Alternative Products

Catalog	Name
BKA99414-01	ICAM-1-IN-1
524167-01	ICAM-1
C2409-48J	CD54 (ICAM-1, ICAM, Icam-1, Intercellular Adhesion Molecule 1) discontinued
510457	Icam-1 discontinued
GWB-53744A	ICAM-1. CD54
MBS852340-01	ICAM-1 Antibody
MBS4380988-01	CD54/ICAM-1
sc-19584	ICAM-1 (1A29)
sc-71292	ICAM-1 (2Q710)

ICAM-1-IN-1

Chemical Information

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