CD54/ICAM-1

• Gene Name:

  [ICAM1]

• NCBI Gene ID:

  3383

• Reactivity:

  Human, Pig

• Storage Conditions:

  Store at 2 to 8 degree C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.

• Specificity:

  Recognizes an 85-115kDa protein (variation with cell type), identified as intercellular adhesion molecule (ICAM-1). It has 7 potential N-linked glycosylation sites. ICAM-1 is a single chain glycoprotein of Ig supergene family, present on unstimulated endothelial cells (EC) and on a variety of other cell types including activated fibroblasts, EC, macrophages, and lymphocytes. ICAM-1 mediates cell adhesion by binding to integrins CD11a/CD18 (leukocyte adhesion molecule, LFA-1) and to CD11b/CD18 (Mac-1). This interaction enhances antigen-specific T-cell activation. ICAM-1 also binds to CD43 and to Plasmodium falciparum infected RBCs. ICAM-1 may also be related to progression and metastasis of tumors.

• Other Gene Names:

  [ICAM1; ICAM1; BB2; CD54; P3.58; ICAM-1]

• Short Name:

  [CD54/ICAM-1]

• Other Product Names:

  [intercellular adhesion molecule 1; Intercellular adhesion molecule 1; intercellular adhesion molecule 1; intercellular adhesion molecule 1; Major group rhinovirus receptor]

• NCBI GI Number:

  167466198

• NCBI Accession Number:

  NP_000192.2

• NCBI GB Accession Number:

  NP_000192.2

• Uniprot Accession Number:

  P05362