Products for Research Use Only
RegisterLogin

5-Methyltetrahydrofolic acid

CAT: 0013-GTR19175562-01Size: 50 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19175562-01Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
5-Methyltetrahydrofolic acid (5-MTHF) is the primary circulating and dietary form of folate. This biologically active cofactor is widely used in research on one-carbon metabolism, methylation processes, and associated in vitro and in vivo studies of neurological and cardiovascular health.
CAS Number
134-35-0
Product Name Alternative
EndogenousMetabolite, Endogenous Metabolite, 5-Methyltetrahydrofolic acid, 5Methyltetrahydrofolic acid, 5-Methyl THF, 5 Methyltetrahydrofolic acid, inhibit, Inhibitor, Human Endogenous Metabolite
Field of Research
Metabolism Research
Purity
98.19% (May vary between batches)
Solubility
DMSO:245 mg/mL (533.23 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.35 mM)
Smiles
[CaH2].CN1C (CNc2ccc (cc2) C (=O) N[C@@H] (CCC (O) =O) C (O) =O) CNc2[nH]c (N) nc (=O) c12
Molecular Formula
C20H25N7O6
Molecular Weight
459.46
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

5-Methyltetrahydrofolic acid

5-methyltetrahydrofolic acid is a methylated derivate of tetrahydrofolate. It is generated by methylenetetrahydrofolate reductase from 5,10-methylenetetrahydrofolate and used to recycle homocysteine back to methionine by 5-methyltetrahydrofolate-homocysteine methyltransferases (also called methionine synthases).

CAS Number134-35-0
PubChem CID135415868
IUPAC Name(2S)-2-[[4-[(2-amino-5-methyl-4-oxo-3,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
Molecular FormulaC20H25N7O6
Molecular Weight459.5
XLogP-0.5
Topological Polar Surface Area198
Hydrogen Bond Donor Count7
Hydrogen Bond Acceptor Count10
Rotatable Bond Count9
Heavy Atom Count33
Formal Charge0
Complexity865
SMILES
CN1C(CNC2=C1C(=O)NC(=N2)N)CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)O)C(=O)O
InChI
InChI=1S/C20H25N7O6/c1-27-12(9-23-16-15(27)18(31)26-20(21)25-16)8-22-11-4-2-10(3-5-11)17(30)24-13(19(32)33)6-7-14(28)29/h2-5,12-13,22H,6-9H2,1H3,(H,24,30)(H,28,29)(H,32,33)(H4,21,23,25,26,31)/t12?,13-/m0/s1
InChIKey
ZNOVTXRBGFNYRX-ABLWVSNPSA-N
Chemical Structure
2D Structure
2D structure of 5-Methyltetrahydrofolic acid
CAS: 134-35-0
CID: 135415868
Formula: C20H25N7O6
MW: 459.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight459.5
XLogP3-0.5
Hydrogen Bond Donor Count7
Hydrogen Bond Acceptor Count10
Rotatable Bond Count9
Exact Mass459.18663154
Monoisotopic Mass459.18663154
Topological Polar Surface Area198 Ų
Heavy Atom Count33
Formal Charge0
Complexity865
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19244132-015-Hydroxydecanoic acid
GTR19238489-015β-Cholanic acid
GTR19235994-015-Iodoisophthalic acid
GTR19350580-01Acid Brown 5
GTR19199791-015-Deazaisofolic acid
GTR19269036-015-Azidopentanoic acid
GTR19259598-015β-Cholanic acid
GTR19169428-015-Methoxysalicylic acid
GTR19168654-015-Aminovaleric acid
GTR19255020-015-Acetylvaleric Acid

Alternative Products

CatalogName
M23504-015-Methyltetrahydrofolic acid
HY-137829-015-Methyltetrahydrofolic acid (disodium)
A18916-5005-Methyltetrahydrofolic acid 500mg
A18916-1005-Methyltetrahydrofolic acid 100mg
A18916-505-Methyltetrahydrofolic acid 50mg
HY-113046S15-Methyltetrahydrofolic acid-13C6
HY-113046S5-Methyltetrahydrofolic acid-13C5
HY-113046R-015-Methyltetrahydrofolic acid (Standard)
sc-3527805-Methyltetrahydrofolic acid calcium salt
sc-214334D5-Methyltetrahydrofolic acid disodium salt

Popular Products