5-Methyltetrahydrofolic acid

Chemical Information
5-methyltetrahydrofolic acid is a methylated derivate of tetrahydrofolate. It is generated by methylenetetrahydrofolate reductase from 5,10-methylenetetrahydrofolate and used to recycle homocysteine back to methionine by 5-methyltetrahydrofolate-homocysteine methyltransferases (also called methionine synthases).
| CAS Number | 134-35-0 |
| PubChem CID | 135415868 |
| IUPAC Name | (2S)-2-[[4-[(2-amino-5-methyl-4-oxo-3,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid |
| Molecular Formula | C20H25N7O6 |
| Molecular Weight | 459.5 |
| XLogP | -0.5 |
| Topological Polar Surface Area | 198 |
| Hydrogen Bond Donor Count | 7 |
| Hydrogen Bond Acceptor Count | 10 |
| Rotatable Bond Count | 9 |
| Heavy Atom Count | 33 |
| Formal Charge | 0 |
| Complexity | 865 |
| Property | Value |
|---|---|
| Molecular Weight | 459.5 |
| XLogP3 | -0.5 |
| Hydrogen Bond Donor Count | 7 |
| Hydrogen Bond Acceptor Count | 10 |
| Rotatable Bond Count | 9 |
| Exact Mass | 459.18663154 |
| Monoisotopic Mass | 459.18663154 |
| Topological Polar Surface Area | 198 Ų |
| Heavy Atom Count | 33 |
| Formal Charge | 0 |
| Complexity | 865 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 1 |
| Undefined Atom Stereocenter Count | 1 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
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