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RGB-286638 free base

CAT: 0013-GTR19174969-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19174969-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RGB-286638 free base is a potent and selective cyclin-dependent kinase (CDK) inhibitor, exhibiting single-digit nM IC50 values against CDK1, CDK2, CDK3, CDK4, CDK5, and CDK9, with reduced activity against CDK6 and CDK7. This tool compound is used in biochemical and cellular research to investigate CDK function in cell cycle progression, transcription, and associated diseases.
CAS Number
784210-88-4
Product Name Alternative
Cyclin dependent kinase, CDK2/cyclinE, CDK3/cyclinE, CDK4/cyclinD1, CDK9/cyclin T1, CDK1/cyclinB1, CDK, Janus kinase, JAK, inhibit, Mitogen-activated protein kinase kinase, MAP2K, MAPKK, MEK, Inhibitor, Glycogen synthase kinase 3, Glycogen synthase kinase-3, GSK3, GSK-3, p35-CDK5, RGB 286638, RGB 286638 free base, RGB286638, RGB-286638, RGB286638 free base, RGB-286638 free base
Field of Research
Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Purity
97.29% (May vary between batches)
Solubility
0.1M HCl:1 mg/mL (1.83 mM) ;15% Solutol HS-15 in Saline:10 mg/mL (18.33 mM) ; DMSO:Slightly soluble
Smiles
COCCN1CCN (Cc2ccc (cc2) -c2n[nH]c3-c4cccc (NC (=O) NN5CCOCC5) c4C (=O) c23) CC1
Molecular Formula
C29H35N7O4
Molecular Weight
545.63
Storage Conditions
-20°C
Notes
For research use only.

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