Products for Research Use Only

CGI-1746

CAT: 0013-GTR19174818-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19174818-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CGI1746 is a potent and highly selective small-molecule inhibitor of Bruton's tyrosine kinase (Btk), exhibiting an IC50 of 1.9 nM. It is a valuable research tool for investigating Btk-related signaling in immunological and oncological research, applicable in both in vitro biochemical assays and in vivo disease models.
CAS Number
910232-84-7
Product Name Alternative
Inhibit, Inhibitor, Autophagy, Btk, BTK, Bruton tyrosine kinase, CGI1746, CGI-1746, CGI 1746
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Purity
97.69% (May vary between batches)
Solubility
H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:33 mg/mL (56.93 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (5.69 mM) ; DMSO:95 mg/mL (163.88 mM)
Smiles
CC1=C (C=CC=C1NC (=O) C2=CC=C (C (C) (C) C) C=C2) C=3N=C (NC4=CC=C (C (=O) N5CCOCC5) C=C4) C (=O) N (C) C3
Molecular Formula
C34H37N5O4
Molecular Weight
579.69
Storage Conditions
-20°C
Notes
For research use only.

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