Products for Research Use Only
RegisterLogin

TGX-221

CAT: 0013-GTR19174787-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19174787-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
TGX-221 is a potent, selective, and cell-permeable inhibitor targeting the PI3K p110β isoform. It is widely used in cancer research to investigate PI3Kβ signaling in both cellular assays and animal models, particularly for studying tumor progression and therapeutic resistance.
CAS Number
663619-89-4
Product Name Alternative
7-Methyl-2-morpholino-9- (1- (phenylamino) ethyl) -4H-pyrido[1,2-a]pyrimidin-4-one
Field of Research
Signal Transduction
Purity
>98%
Form
Powder
Solubility
Soluble in DMSO (up to at least 10 mg/ml)
Smiles
CC (Nc1ccccc1) c1cc (C) cn2c1nc (cc2=O) N1CCOCC1
Molecular Formula
C21H24N4O2
Molecular Weight
364.5
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
9- (1-Anilinoethyl) -7-methyl-2-morpholino-4-ylpyrido[1,2-a]pyrimidin-4-one

Chemical Information

Tgx-221

9-(1-anilinoethyl)-7-methyl-2-(4-morpholinyl)-4-pyrido[1,2-a]pyrimidinone is a pyridopyrimidine.

CAS Number663619-89-4
PubChem CID9907093
IUPAC Name9-(1-anilinoethyl)-7-methyl-2-morpholin-4-ylpyrido[1,2-a]pyrimidin-4-one
Molecular FormulaC21H24N4O2
Molecular Weight364.4
XLogP1.9
Topological Polar Surface Area57.2
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count4
Heavy Atom Count27
Formal Charge0
Complexity710
SMILES
CC1=CN2C(=O)C=C(N=C2C(=C1)C(C)NC3=CC=CC=C3)N4CCOCC4
InChI
InChI=1S/C21H24N4O2/c1-15-12-18(16(2)22-17-6-4-3-5-7-17)21-23-19(13-20(26)25(21)14-15)24-8-10-27-11-9-24/h3-7,12-14,16,22H,8-11H2,1-2H3
InChIKey
CPRAGQJXBLMUEL-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Tgx-221
CAS: 663619-89-4
CID: 9907093
Formula: C21H24N4O2
MW: 364.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight364.4
XLogP31.9
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count4
Exact Mass364.18992602
Monoisotopic Mass364.18992602
Topological Polar Surface Area57.2 Ų
Heavy Atom Count27
Formal Charge0
Complexity710
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19199572-01TGX-115
GTR19199571-01TGX-155
GTR19218209-01HLDA-221
GTR19192682-01SCH-221
GTR19198256-01AMG-221
GTR19245519-01Kryptofix 221
GTR19194247ISS-221
GTR19273344-01DHW-221
GTR19195983ABBV-221
GTR19036844-01PEN-221

Alternative Products

CatalogName
HY-10114-01TGX-221
MBS132162-01TGX 221

Popular Products