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NU6140

CAT: 0013-GTR19174791-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19174791-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NU6140 is a potent and selective small molecule inhibitor of CDK2-cyclin A, with additional activity against Aurora A and B kinases. It induces apoptosis and demonstrates anti-cancer properties in cellular studies, making it a useful research tool for investigating cell cycle regulation and oncology.
CAS Number
444723-13-1
Product Name Alternative
NU 6140, NU6140, NU-6140, Inhibitor, inhibit, CDK4/CyclinD, CDK4-Cyclin D, cdk5/p25, cdk7/cyclinH, cdk7-cyclin H, cdk5-p25, CDK, CDK1-Cyclin B, CDK1/CyclinB, cdk2-cyclin A, cdk2/cyclinA, Cyclin dependent kinase, Aurora A, Aurora B, AuroraKinase, Aurora Kinase
Field of Research
Cell Biology, Epigenetics & Chromatin
Purity
98.04% (May vary between batches)
Solubility
DMSO:250 mg/mL (591.69 mM)
Smiles
CCN (CC) C (=O) c1ccc (Nc2nc (OCC3CCCCC3) c3[nH]cnc3n2) cc1
Molecular Formula
C23H30N6O2
Molecular Weight
422.52
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

NU6140
CAS Number444723-13-1
PubChem CID10202471
IUPAC Name4-[[6-(cyclohexylmethoxy)-7H-purin-2-yl]amino]-N,N-diethylbenzamide
Molecular FormulaC23H30N6O2
Molecular Weight422.5
XLogP4.8
Topological Polar Surface Area96
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count8
Heavy Atom Count31
Formal Charge0
Complexity560
SMILES
CCN(CC)C(=O)C1=CC=C(C=C1)NC2=NC3=C(C(=N2)OCC4CCCCC4)NC=N3
InChI
InChI=1S/C23H30N6O2/c1-3-29(4-2)22(30)17-10-12-18(13-11-17)26-23-27-20-19(24-15-25-20)21(28-23)31-14-16-8-6-5-7-9-16/h10-13,15-16H,3-9,14H2,1-2H3,(H2,24,25,26,27,28)
InChIKey
XHEQSRJCJTWWAH-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of NU6140
CAS: 444723-13-1
CID: 10202471
Formula: C23H30N6O2
MW: 422.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight422.5
XLogP34.8
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count8
Exact Mass422.24302422
Monoisotopic Mass422.24302422
Topological Polar Surface Area96 Ų
Heavy Atom Count31
Formal Charge0
Complexity560
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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Alternative Products

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HY-107419-01NU6140
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A20264-5NU6140 5mg
A20264-200NU6140 200mg
A20264-25NU6140 25mg
A20264-100NU6140 100mg
A20264-50NU6140 50mg
A20264-2NU6140 2mg
A20264-10mM-DNU6140 10mM * 1mL in DMSO

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