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NU6300

CAT: 0013-GTR19203724Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19203724Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NU6300 is a covalent, ATP-competitive CDK2 inhibitor (IC50=0.16 μM) that blocks Rb phosphorylation. It also acts as a GSDMD inhibitor by preventing Cys-191 cleavage and palmitoylation, thereby suppressing NLRP3 activation pathways. This dual activity makes it a valuable research tool for studying cell cycle, transcription, and inflammatory diseases like colitis and sepsis in experimental models.
CAS Number
2070015-09-5
Field of Research
Cell Biology, Immunology & Inflammation, Signal Transduction
Purity
96.08% (May vary between batches)
Smiles
C=CS (=O) (=O) c1ccc (Nc2nc (OCC3CCCCC3) c3nc[nH]c3n2) cc1
Molecular Formula
C20H23N5O3S
Molecular Weight
413.49
Storage Conditions
-20°C
Notes
For research use only.

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