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AKT1 (Proto-Oncogene)

CAT: 0544-MBS439937-01Size: 0.02 mg (With BSA & Azide at 0.2mg/mL)Dry Ice: NoHazardous: No
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CAT#:0544-MBS439937-01Size:0.02 mg (With BSA & Azide at 0.2mg/mL)
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Gene Name
[AKT1]
NCBI Gene ID
207
Reactivity
Human. Others not known
Storage Conditions
Antibody with azide - store at 2 to 8 °C.
Antibody without azide - store at -20 to -80 °C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
Recognizes a protein of 62kDa, which is identified as AKT1The serine/threonine kinase Akt family contains several members, including Akt1 (also designated PKB or RacPK), Akt2 (also designated PKB? or RacPK-?) and Akt 3 (also designated PKB? or thyoma viral proto-oncogene 3), which exhibit sequence homology with the protein kinase A and C families and are encoded by the c-Akt proto-oncogene. All members of the Akt family have a Pleckstrin homology domain. Akt1 and Akt2 are activated by PDGF stimulation. This activation is dependent on PDGFR-? tyrosine residues 740 and 751, which bind the subunit of the phosphatidylinositol 3-kinase (PI 3-kinase) complex. Activation of Akt1 by insulin or insulin-growth factor-1(IGF-1) results in phosphorylation of both Thr 308 and Ser 473. Akt proteins become phosphorylated and activated in insulin/IGF-1-stimulated cells by an upstream kinase(s), and the activation of Akt1 and Akt2 is inhibited by the PI kinase inhibitor wortmannin.
Other Gene Names
[AKT1; AKT1; AKT; PKB; RAC; CWS6; PRKBA; PKB-ALPHA; RAC-ALPHA; PKB; RAC; PKB; PKB alpha]
Short Name
[AKT1]
Other Product Names
[RAC-alpha serine/threonine-protein kinase; RAC-alpha serine/threonine-protein kinase; RAC-alpha serine/threonine-protein kinase; AKT serine/threonine kinase 1; Protein kinase B; PKB; Protein kinase B alpha; PKB alpha; Proto-oncogene c-Akt; RAC-PK-alpha]
NCBI GI Number
62241013
NCBI Accession Number
NP_001014431.1
NCBI GB Accession Number
NM_001014431.1
Uniprot Accession Number
P31749

Alternative Products

CatalogName
031752Akt1, NT (Akt1, Akt, Rac, RAC-alpha serine/threonine-protein kinase, AKT1 kinase, Protein kinase B, Protein kinase B alpha, Proto-oncogene c-Akt, RAC-PK-alpha, Thymoma viral proto-oncogene)
031752-BiotinAkt1, NT (Akt1, Akt, Rac, RAC-alpha serine/threonine-protein kinase, AKT1 kinase, Protein kinase B, Protein kinase B alpha, Proto-oncogene c-Akt, RAC-PK-alpha, Thymoma viral proto-oncogene) (Biotin)
031752-PEAkt1, NT (Akt1, Akt, Rac, RAC-alpha serine/threonine-protein kinase, AKT1 kinase, Protein kinase B, Protein kinase B alpha, Proto-oncogene c-Akt, RAC-PK-alpha, Thymoma viral proto-oncogene) (PE) discontinued
031752-APCAkt1, NT (Akt1, Akt, Rac, RAC-alpha serine/threonine-protein kinase, AKT1 kinase, Protein kinase B, Protein kinase B alpha, Proto-oncogene c-Akt, RAC-PK-alpha, Thymoma viral proto-oncogene) (APC) discontinued
031752-FITCAkt1, NT (Akt1, Akt, Rac, RAC-alpha serine/threonine-protein kinase, AKT1 kinase, Protein kinase B, Protein kinase B alpha, Proto-oncogene c-Akt, RAC-PK-alpha, Thymoma viral proto-oncogene) (FITC) discontinued
031752-APAkt1, NT (Akt1, Akt, Rac, RAC-alpha serine/threonine-protein kinase, AKT1 kinase, Protein kinase B, Protein kinase B alpha, Proto-oncogene c-Akt, RAC-PK-alpha, Thymoma viral proto-oncogene) (AP) discontinued
031752-ML490Akt1, NT (Akt1, Akt, Rac, RAC-alpha serine/threonine-protein kinase, AKT1 kinase, Protein kinase B, Protein kinase B alpha, Proto-oncogene c-Akt, RAC-PK-alpha, Thymoma viral proto-oncogene) (MaxLight 490) discontinued
031752-ML405Akt1, NT (Akt1, Akt, Rac, RAC-alpha serine/threonine-protein kinase, AKT1 kinase, Protein kinase B, Protein kinase B alpha, Proto-oncogene c-Akt, RAC-PK-alpha, Thymoma viral proto-oncogene) (MaxLight 405) discontinued
031752-ML750Akt1, NT (Akt1, Akt, Rac, RAC-alpha serine/threonine-protein kinase, AKT1 kinase, Protein kinase B, Protein kinase B alpha, Proto-oncogene c-Akt, RAC-PK-alpha, Thymoma viral proto-oncogene) (MaxLight 750) discontinued
031752-ML550Akt1, NT (Akt1, Akt, Rac, RAC-alpha serine/threonine-protein kinase, AKT1 kinase, Protein kinase B, Protein kinase B alpha, Proto-oncogene c-Akt, RAC-PK-alpha, Thymoma viral proto-oncogene) (MaxLight 550) discontinued