RET Proto-oncogene

CAT: 0544-MBS4381222-01Size: 0.02 mg (With BSA & Azide at 0.2mg/mL)Dry Ice: NoHazardous: No
CAT#:0544-MBS4381222-01Size:0.02 mg (With BSA & Azide at 0.2mg/mL)
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Gene Name
[RET]
NCBI Gene ID
5979
Reactivity
Human
Storage Conditions
Antibody with azide: store at 2 to 8 degree C.
Antibody without azide: store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
The Ret proto-oncogene is structurally related to the growing family of tyrosine kinase transmembrane receptors and is involved in GDNF signaling. RET expression is reported in several regions of the central nervous system; in the developing cranial nerve ganglia and a subset of cells within dorsal root ganglia, in motor neurons in the spinal cord and hindbrain, in neuro-retina and the growing tips of the renal collecting ducts in developing kidney.Alterations in RETgene are associated with diseases including papillary thyroid carcinoma, multiple endocrine neoplasia (type 2A and 2B), familial medullary thyroid carcinoma, and a congenital developmental disorder known as Hirschsprung's disease.
Other Gene Names
[RET; RET; PTC; MTC1; HSCR1; MEN2A; MEN2B; CDHF12; CDHR16; RET-ELE1; CDHF12; CDHR16; PTC; RET51]
Short Name
[RET Proto-oncogene]
Other Product Names
[proto-oncogene tyrosine-protein kinase receptor Ret isoform c; Proto-oncogene tyrosine-protein kinase receptor Ret; proto-oncogene tyrosine-protein kinase receptor Ret; ret proto-oncogene; Cadherin family member 12; Proto-oncogene c-Ret]
NCBI GI Number
10862701
NCBI Accession Number
NP_065681.1
NCBI GB Accession Number
NP_065681.1
Uniprot Accession Number
P07949

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