Podoplanin (PDPN) (Lymphatic Endothelial & Mesothelial Marker)

Podoplanin (PDPN) (Lymphatic Endothelial & Mesothelial Marker)

• Gene Name: [PDPN]
• NCBI Gene ID: 10630
• Reactivity: Human. Others not known.
• Storage Conditions: Antibody with azide - store at 2 to 8 °C.
  Antibody without azide - store at -20 to -80 °C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.
• Specificity: It recognizes a muco-protein of 38-43kDa, which is identified Podoplanin (PDPN). It localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells. As a regulator of the lymphatic endothelium, podoplanin probably plays a role in maintaining the unique shape of podocytes. It is selectively expressed in lymphatic endothelium as well as lymphoangiomas, Kaposi sarcomas, and in a subset of angiosarcomas with probable lymphatic differentiation. Recent studies have also shown podoplanin to be a highly sensitive and relatively specific marker for epithelioid mesothelioma. Therefore, it can be used in a panel to distinguish mesotheliomas or mesothelial cells from pulmonary carcinomas.
• Other Gene Names: [PDPN; PDPN; T1A; GP36; GP40; Gp38; OTS8; T1A2; TI1A; T1A-2; AGGRUS; HT1A-1; PA2.26; PICD]
• Short Name: [Podoplanin (PDPN)]
• Other Product Names: [podoplanin isoform c; Podoplanin; podoplanin; podoplanin; Aggrus]
• NCBI GI Number: 54792060
• NCBI Accession Number: NP_001006625.1
• NCBI GB Accession Number: NM_001006624.1
• Uniprot Accession Number: Q86YL7