Podoplanin (PDPN) (Lymphatic Endothelial & Mesothelial Marker)

• Gene Name:

  [PDPN]

• NCBI Gene ID:

  10630

• Reactivity:

  Human. Others not known.

• Storage Conditions:

  Antibody with azide - store at 2 to 8 °C.
  Antibody without azide - store at -20 to -80 °C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.

• Specificity:

  It recognizes a muco-protein of 38-43kDa, which is identified Podoplanin (PDPN). It localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells. As a regulator of the lymphatic endothelium, podoplanin probably plays a role in maintaining the unique shape of podocytes. It is selectively expressed in lymphatic endothelium as well as lymphoangiomas, Kaposi sarcomas, and in a subset of angiosarcomas with probable lymphatic differentiation. Recent studies have also shown podoplanin to be a highly sensitive and relatively specific marker for epithelioid mesothelioma. Therefore, it can be used in a panel to distinguish mesotheliomas or mesothelial cells from pulmonary carcinomas.

• Other Gene Names:

  [PDPN; PDPN; T1A; GP36; GP40; Gp38; OTS8; T1A2; TI1A; T1A-2; AGGRUS; HT1A-1; PA2.26; PICD]

• Short Name:

  [Podoplanin (PDPN)]

• Other Product Names:

  [podoplanin isoform c; Podoplanin; podoplanin; podoplanin; Aggrus]

• NCBI GI Number:

  54792060

• NCBI Accession Number:

  NP_001006625.1

• NCBI GB Accession Number:

  NM_001006624.1

• Uniprot Accession Number:

  Q86YL7