Binimetinib

CAT: 0013-GTR19173803-01Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19173803-01Size:5 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

Binimetinib (ARRY-162) is an orally bioavailable, selective MEK1/2 inhibitor (IC50=12 nM) . It exhibits antitumor activity and is used in research for unresectable or BRAF V600E/K mutant metastatic melanoma. Its application extends to in vitro signaling studies and in vivo xenograft models investigating MAPK pathway inhibition.

CAS Number

606143-89-9

Product Name Alternative

ARRY-162; MEK162

Field of Research

Cell Biology, Pharmacology & Drug Discovery, Signal Transduction

Purity

>98%

Bioactivity

MEK1/2 inhibitor

Form

Powder

Solubility

Soluble in DMSO (up to at least 25 mg/ml)

Smiles

Cn1cnc2c (F) c (Nc3ccc (Br) cc3F) c (cc12) C (=O) NOCCO

Molecular Formula

C17H15BrF2N4O3

Molecular Weight

441.23

Storage Conditions

-20°C

Notes

For research use only.

Other Product Names

6- (4-Bromo-2-fluoroanilino) -7-fluoro-N- (2-hydroxyethoxy) -3-methylbenzimidazole-5-carboxamide

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Catalog	Name
bs-83020C-01	Binimetinib
C12377-1g	Binimetinib (MEK162)
HY-15202S1-01	Binimetinib-d3
TRC-B655730-250MG	Binimetinib Hydroxylamine
TRC-B775560-5MG	Binimetinib Glucuronide
CS-O-44733	Binimetinib-d4
HY-15202R-01	Binimetinib (Standard)
SD5951-10mM	Binimetinib (MEK inhibitor)
TRC-N890670-5MG	N-Nitroso Binimetinib
TRC-D427820-50MG	N-Desmethyl Binimetinib

Binimetinib

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