Products for Research Use Only
RegisterLogin

LY83583

CAT: 0013-GTR19174068-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19174068-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
LY83583 is a potent and selective competitive inhibitor of soluble guanylate cyclase (sGC), exhibiting an IC50 of 2 μM. This small molecule is widely used in cardiovascular and neurological research to investigate the cGMP signaling pathway in both cellular and animal models.
CAS Number
91300-60-6
Product Name Alternative
6-Anilino-5,8-quinolinedione, 6-anilinoquinoline-5,8-dione, LY 83583, LY-83583, LY83583, Guanylatecyclase, Guanylate cyclase
Field of Research
Pharmacology & Drug Discovery
Purity
98.20% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (4 mM) ; DMSO:2.51 mg/mL (10.03 mM)
Smiles
O=C1C=C (Nc2ccccc2) C (=O) c2cccnc12
Molecular Formula
C15H10N2O2
Molecular Weight
250.25
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

6-(Phenylamino)-5,8-quinolinedione

6-anilino-5,8-quinolinedione is a quinolone that is quinoline-5,8-dione in which the hydrogen at position 6 is replaced by an anilino group. It has a role as an antineoplastic agent and an EC 4.6.1.2 (guanylate cyclase) inhibitor. It is a quinolone, a member of p-quinones, an aromatic amine and an aminoquinoline.

CAS Number91300-60-6
PubChem CID3976
IUPAC Name6-anilinoquinoline-5,8-dione
Molecular FormulaC15H10N2O2
Molecular Weight250.25
XLogP2.5
Topological Polar Surface Area59.1
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count2
Heavy Atom Count19
Formal Charge0
Complexity410
SMILES
C1=CC=C(C=C1)NC2=CC(=O)C3=C(C2=O)C=CC=N3
InChI
InChI=1S/C15H10N2O2/c18-13-9-12(17-10-5-2-1-3-6-10)15(19)11-7-4-8-16-14(11)13/h1-9,17H
InChIKey
GXIJYWUWLNHKNW-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 6-(Phenylamino)-5,8-quinolinedione
CAS: 91300-60-6
CID: 3976
Formula: C15H10N2O2
MW: 250.25
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight250.25
XLogP32.5
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count2
Exact Mass250.074227566
Monoisotopic Mass250.074227566
Topological Polar Surface Area59.1 Ų
Heavy Atom Count19
Formal Charge0
Complexity410
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
406381LY83583
HY-W013386R-01LY83583 (Standard)
217526LY 83583 (LY83583, 6-Anilino-5,8-quinolinequinone)

Popular Products