J-147

CAT: 0013-GTR19173530-01Size: 5 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0013-GTR19173530-01Size:5 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Description

J-147 is a synthetic curcumin derivative developed as a neuroprotective and neurogenic research compound. It has shown efficacy in preclinical models of aging, Alzheimer's disease, and diabetic neuropathy, impacting multiple relevant pathways. Studies include both in vitro assays and in vivo experiments using accelerated aging mouse models.

CAS Number

1146963-51-0

Product Name Alternative

SLC6A3, oxidase, transporte, Alzheimer, barrier, BBB, BDNF, brain, blood, disease, dopamine, DopamineReceptor, Dopamine Transporter, Dopamine Receptor, DAT, inhibit, J147, J-147, J 147, MonoamineOxidase, Monoamine Oxidase, monoamine, neuroprotective, MAO, MAO B, Inhibitor, Epigenetic Reader Domain, EpigeneticReaderDomain

Field of Research

Epigenetics & Chromatin, Neuroscience, Pharmacology & Drug Discovery

Purity

99.30% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.85 mM) ; DMSO:45 mg/mL (128.45 mM)

Smiles

COc1cccc (\C=N\N (C (=O) C (F) (F) F) c2ccc (C) cc2C) c1

Molecular Formula

C18H17F3N2O2

Molecular Weight

350.33

Storage Conditions

-20°C

Notes

For research use only.

Chemical Information

J147

J147 is an anilide.

CAS Number	1146963-51-0
PubChem CID	25229652
IUPAC Name	N-(2,4-dimethylphenyl)-2,2,2-trifluoro-N-[(E)-(3-methoxyphenyl)methylideneamino]acetamide
Molecular Formula	C18H17F3N2O2
Molecular Weight	350.3
XLogP	4.7
Topological Polar Surface Area	41.9
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	4
Heavy Atom Count	25
Formal Charge	0
Complexity	481

SMILES

CC1=CC(=C(C=C1)N(C(=O)C(F)(F)F)/N=C/C2=CC(=CC=C2)OC)C

InChI

InChI=1S/C18H17F3N2O2/c1-12-7-8-16(13(2)9-12)23(17(24)18(19,20)21)22-11-14-5-4-6-15(10-14)25-3/h4-11H,1-3H3/b22-11+

InChIKey

HYMZAYGFKNNHDN-SSDVNMTOSA-N

Chemical Structure

2D Structure

CAS: 1146963-51-0

CID: 25229652

Formula: C18H17F3N2O2

MW: 350.3

Interactive 3D Structure

Loading 3D structure...

View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	350.3
XLogP3	4.7
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	4
Exact Mass	350.12421228
Monoisotopic Mass	350.12421228
Topological Polar Surface Area	41.9 Å²
Heavy Atom Count	25
Formal Charge	0
Complexity	481
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	1
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Related Products

Catalog	Name
GTR19249717-01	EGFR-IN-147
GTR19218704-01	Anticancer agent 147
GTR18985492-01	FGF2 (147) Protein
GTR19301282-01	Pigment Red 147
GTR19301252-01	Pigment Yellow 147
GTR19175492-01	Compound 147 (AA147)
GTR18077553	Transmembrane protein 147 antibody
GTR19068218-01	Influenza NP (147 - 155)
GTR19036918-01	Influenza NP (147-155)
GTR18903668-01	Influenza NP (147-155)

Alternative Products

Catalog	Name
TRC-J210300-100MG	J 147
BUP13417-01	J-147
FH23825-01	JWH 147
TQA12174	AA 147
cyt-1130-01	bFGF2 (147)
T9901A-1819-01	ABT-147
9401-5	XL-147
8077/2	MS 147
cyt-557-01	FGF2 (147)
FX137599-01	XL 147

J-147

Chemical Information

Related Products

Alternative Products

Popular Products