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Defactinib

CAT: 0013-GTR19173517-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19173517-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Defactinib (VS-6063) is a second-generation, ATP-competitive FAK inhibitor that blocks autophosphorylation at Tyr397. It demonstrates antitumor activity in research, showing efficacy in in vitro cell proliferation assays and in vivo models of cancer metastasis and tumor growth inhibition.
CAS Number
1073154-85-4
Product Name Alternative
PF-04554878; VS-6063
Field of Research
Cancer Biology, Immunology & Inflammation
Purity
>98%
Bioactivity
Potent FAK inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to at least 25 mg/ml)
Smiles
CNC (=O) c1ccc (Nc2ncc (c (NCc3nccnc3N (C) S (C) (=O) =O) n2) C (F) (F) F) cc1
Molecular Formula
C20H21F3N8O3S
Molecular Weight
510.50
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
N-Methyl-4-[[4-[[3-[methyl (methylsulfonyl) amino]pyrazin-2-yl]methylamino]-5- (trifluoromethyl) pyrimidin-2-yl]aminl]benzamide

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B4800-5Defactinib
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HY-12289R-01Defactinib (Standard)

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