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Nutlin-3a

CAT: 0013-GTR19171818-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19171818-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Nutlin-3a is the biologically active enantiomer of Nutlin-3, functioning as a potent and selective MDM2 antagonist that disrupts the MDM2-p53 interaction. This stabilization and activation of p53 underpins its utility in cancer research, demonstrating antitumor activity in both cellular assays and in vivo models.
CAS Number
675576-98-4
Product Name Alternative
Apoptosis, Autophagy, carcinomas, (-) -Nutlin-3, (−) -Nutlin-3, E1 activating enzyme, E2Enzyme, E3 Enzyme, E2 Enzyme, E2 conjugating enzyme, E1/E2/E3 Enzyme, E1 Enzyme, E1Enzyme, E3 ligating enzyme, E3Enzyme, Inhibitor, MDM-2/p53, inhibit, p53, p53/MDM2, Nutlin 3a, Nutlin-3, Nutlin3a, Nutlin-3a, Nutlin-3a chiral, ovarian, Rebemadlin, Ubiquitin ligase, Ubiquitin conjugating enzyme, Ubiquitin activating enzyme
Field of Research
Cell Biology, Protein Biochemistry
Purity
95.62% (May vary between batches)
Solubility
Ethanol:58.2 mg/mL (100.09 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.44 mM) ; DMSO:55 mg/mL (94.58 mM)
Smiles
COc1ccc (C2=N[C@H] ([C@H] (N2C (=O) N2CCNC (=O) C2) c2ccc (Cl) cc2) c2ccc (Cl) cc2) c (OC (C) C) c1
Molecular Formula
C30H30Cl2N4O4
Molecular Weight
581.49
Storage Conditions
-20°C
Notes
For research use only.

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Alternative Products

CatalogName
MBS385839-01Nutlin 3a
MBS132120-01Nutlin-3a
A3671-5.1Nutlin-3a chiral
A11501-50Nutlin 3a 50mg
A11501-25Nutlin 3a 25mg
HY-10029RNutlin-3a (Standard)
A11501-100Nutlin 3a 100mg
A11501-10Nutlin 3a 10mg
A11501-2Nutlin 3a 2mg
A11501-1Nutlin 3a 1mg

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