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YM-201636

CAT: 0013-GTR19171733-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19171733-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
YM201636 is a potent and selective PIKfyve inhibitor with an IC50 of 33 nM. It exhibits minimal activity against p110α and no effect on the yeast orthologue Fab1. This compound is a valuable research tool for studying lysosomal function and autophagy in cellular and animal models of related diseases.
CAS Number
371942-69-7
Product Name Alternative
P110α, Inhibitor, Influenza Virus, InfluenzaVirus, inhibit, Fab1, Autophagy, Phosphoinositide 3-kinase, PIKfyve, PI3K, YM201636, YM-201636, YM 201636
Field of Research
Cell Biology, Infectious Disease & Virology, Signal Transduction
Purity
93.28% (May vary between batches)
Solubility
DMSO:13.33 mg/mL (28.51 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.28 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble)
Smiles
Cl.Nc1ccc (cn1) C (=O) Nc1cccc (c1) -c1nc (N2CCOCC2) c2oc3ncccc3c2n1
Molecular Formula
C25H21N7O3
Molecular Weight
467.48
Storage Conditions
-20°C
Notes
For research use only.

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