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Avitinib

CAT: 0013-GTR19171541-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19171541-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Avitinib (AC0010) is an orally bioavailable, irreversible inhibitor that selectively targets mutant epidermal growth factor receptor (EGFR), including the T790M resistance mutation. It is used in oncology research to study tumor growth inhibition in EGFR-mutated models, with applications in both in vitro cellular assays and in vivo xenograft experiments.
CAS Number
1557267-42-1
Product Name Alternative
AC 0010, AC0010, AC-0010, Abivertinib, Avitinib, Btk, BTK, Bruton tyrosine kinase, Epidermal growth factor receptor, ErbB-1, EGFR, Inhibitor, HER1, inhibit, JAK3
Field of Research
Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Purity
99.81% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.77 mM) ; DMSO:88 mg/mL (180.5 mM)
Smiles
CN1CCN (CC1) c1ccc (Nc2nc (Oc3cccc (NC (=O) C=C) c3) c3cc[nH]c3n2) cc1F
Molecular Formula
C26H26FN7O2
Molecular Weight
487.53
Storage Conditions
-20°C
Notes
For research use only.

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