Products for Research Use Only
RegisterLogin

Avitinib

CAT: 0026-B2995-5Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0026-B2995-5Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Avitinib is a pyrrolopyrimidine-based, irreversible inhibitor of the epidermal growth factor receptor (EGFR) receptor tyrosine kinase. It inhibits EGFR L858R/T790M double mutations with an IC₅₀ value of 0.18 nM which is nearly 43-fold potent over wild-type EGFR (IC₅₀ value of 7.68 nM) in kinase assays. In a xenograft model, oral administration at a daily dose of 500 mg/kg results in complete remission of tumors with EGFR-active and T790M mutations.
Shipping Conditions
RT
Storage Conditions
-20ºC
Shelf Life
36 months

Alternative Products

CatalogName
MBS578129Avitinib
T3721-01Avitinib maleate
MBS3841805-01Avitinib (AC0010)
S8741-01Avitinib (Abivertinib)
HY-178286Avitinib-methyl
HY-19816A-01Avitinib (maleate)

Popular Products