Products for Research Use Only

Mivebresib

CAT: 0013-GTR19170947-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19170947-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Mivebresib (ABBV-075) is a potent and selective BET bromodomain inhibitor that displaces BET proteins from acetylated chromatin, suppressing oncogenic transcription factors like MYC and TMPRSS2-ETS fusions. It demonstrates robust antitumor activity in preclinical models of hematologic malignancies and solid tumors, supporting its investigation in cancer research.
CAS Number
1445993-26-9
Product Name Alternative
Inhibitor, EpigeneticReaderDomain, Epigenetic Reader Domain, inhibit, Mivebresib, ABBV 075, ABBV-075, ABBV075, Apoptosis, BET
Field of Research
Cell Biology, Epigenetics & Chromatin
Purity
97.17% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.18 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:250 mg/mL (544.11 mM)
Smiles
O (C1=C (C=2C3=C (C (=O) N (C) C2) NC=C3) C=C (NS (CC) (=O) =O) C=C1) C4=C (F) C=C (F) C=C4
Molecular Formula
C22H19F2N3O4S
Molecular Weight
459.47
Storage Conditions
-20°C
Notes
For research use only.

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