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Polyphyllin I

CAT: 0013-GTR19170681-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19170681-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Polyphyllin D is a bioactive steroidal saponin with potent anticancer activity, inducing mitochondrial-mediated apoptosis and overcoming drug resistance in vitro. Its mechanisms include Bcl-2 downregulation, Bax upregulation, and caspase-3 activation, alongside noted anti-angiogenic and erythrocyte toxicity effects, supporting its research in oncology and hematology studies.
CAS Number
50773-41-6
Product Name Alternative
Mammalian target of Rapamycin, Inhibitor, inhibit, JNK, mTOR, Akt, apoptosis, Apoptosis, Autophagy, Protein kinase B, Polyphyllin I, PDK-1, PDK1, PKB
Field of Research
Cell Biology, Signal Transduction
Purity
98.00% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween-80+45% Saline:1 mg/mL (1.17 mM) ; DMSO:250 mg/mL (292.39 mM)
Smiles
[H][C@]12C[C@@]3 ([H]) [C@]4 ([H]) CC=C5C[C@H] (CC[C@]5 (C) [C@@]4 ([H]) CC[C@]3 (C) [C@@]1 ([H]) [C@H] (C) [C@@]1 (CC[C@@H] (C) CO1) O2) O[C@]1 ([H]) O[C@H] (CO) [C@@H] (O[C@]2 ([H]) O[C@@H] (CO) [C@H] (O) [C@H]2O) [C@H] (O) [C@H]1O[C@]1 ([H]) O[C@@H] (C) [C@H] (O) [C@@H] (O) [C@H]1O
Molecular Formula
C44H70O16
Molecular Weight
855.02
Storage Conditions
-20°C
Notes
For research use only.

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N1924-20Polyphyllin A
TP049263Polyphyllin Ⅵ
TP049264Polyphyllin Ⅶ
N2818-20Polyphyllin VII
CS-BS-00226Polyphyllin I
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