Polyphyllin C

CAT: 0804-HY-W019829Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-W019829Size:1 mg
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Description
Polyphyllin C (compound 2) is a spirostanol saponin. Polyphyllin C exhibits mild (IC50=36.87 µM) activities against the tyrosinase and moderate (IC50=1.59 µg/mL) antileishmanial activities[1][2].
CAS Number
[76296-71-4]
UNSPSC
12352005
Target
Parasite; Tyrosinase
Type
Natural Products
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/polyphyllin-c.html
Solubility
10 mM in DMSO
Smiles
C[C@@H]1CC[C@]2(OC1)[C@@H](C)[C@H]3[C@H](C[C@@H]4[C@]3(C)CC[C@H]5[C@H]4CC=C6[C@]5(C)CC[C@H](O[C@H]7[C@H](O)[C@@H](O[C@H]8[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O8)[C@H](O)[C@@H](CO)O7)C6)O2
Molecular Formula
C39H62O12
Molecular Weight
722.90
References & Citations
[1]Devkota KP, et, al. Tyrosinase inhibitory and antileishmanial constituents from the rhizomes of Paris polyphylla. Nat Prod Res. 2007 Apr;21 (4) :321-7.|[2]Singh SB, et, al. Spirostanol saponins from Paris polyphylla, structures of polyphyllin C, D, E and F. Phytochemistry.1980; 21 (12) : 2925-2929.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Leishmania

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