Products for Research Use Only
RegisterLogin

BRD 4354

CAT: 0013-GTR19178113-03Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19178113-03Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
BRD 4354 is a small molecule inhibitor of HDAC5 (IC50 = 0.85 μM) and HDAC9 (IC50 = 1.88 μM) . It serves as a research tool for investigating the roles of these class IIa HDACs in cardiac remodeling, neurological function, and muscle differentiation in in vitro studies.
CAS Number
315698-07-8
Product Name Alternative
Inhibit, Histone deacetylases, Inhibitor, HDAC, HDAC9, HDAC5, BRD 4354, BRD4354, BRD-4354
Field of Research
Epigenetics & Chromatin, Molecular Biology
Purity
99.08% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.61 mM) ; DMSO:10 mg/mL (26.12 mM)
Smiles
CCN1CCN (CC1) C (c1cccnc1) c1cc (Cl) c2cccnc2c1O
Molecular Formula
C21H23ClN4O
Molecular Weight
382.89
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

5-Chloro-7-((4-ethylpiperazin-1-yl)(pyridin-3-yl)methyl)quinolin-8-ol

5-chloro-7-[(4-ethyl-1-piperazinyl)-(3-pyridinyl)methyl]-8-quinolinol is a member of quinolines and an organochlorine compound.

CAS Number315698-07-8
PubChem CID3516032
IUPAC Name5-chloro-7-[(4-ethylpiperazin-1-yl)-pyridin-3-ylmethyl]quinolin-8-ol
Molecular FormulaC21H23ClN4O
Molecular Weight382.9
XLogP3.1
Topological Polar Surface Area52.5
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count4
Heavy Atom Count27
Formal Charge0
Complexity473
SMILES
CCN1CCN(CC1)C(C2=CN=CC=C2)C3=CC(=C4C=CC=NC4=C3O)Cl
InChI
InChI=1S/C21H23ClN4O/c1-2-25-9-11-26(12-10-25)20(15-5-3-7-23-14-15)17-13-18(22)16-6-4-8-24-19(16)21(17)27/h3-8,13-14,20,27H,2,9-12H2,1H3
InChIKey
XAFSFXYJOJWLJD-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 5-Chloro-7-((4-ethylpiperazin-1-yl)(pyridin-3-yl)methyl)quinolin-8-ol
CAS: 315698-07-8
CID: 3516032
Formula: C21H23ClN4O
MW: 382.9
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight382.9
XLogP33.1
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count4
Exact Mass382.1560391
Monoisotopic Mass382.1560391
Topological Polar Surface Area52.5 Ų
Heavy Atom Count27
Formal Charge0
Complexity473
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19206383-01BRD-K98645985
GTR19259046-01BRD-4592
GTR19239695-01BRD-K44839765
GTR19237935-01BRD-810
GTR19210325-01BRD-K25923209
GTR19209475-01BRD-7880
GTR19259941-01BRD-K98645985
GTR19175009-01BRD 7116
GTR19258363-01BRD-9327
GTR19240013-01BRD-K20733377

Alternative Products

CatalogName
HY-112719-01BRD 4354
HY-112719BBRD 4354 (ditrifluoroacetate)
A19532-50BRD 4354 50mg
A19532-100BRD 4354 100mg
PC1006305-01BRD 4354 ditrifluoroacetate
A19532-500BRD 4354 500mg
A19532-5BRD 4354 5mg
A19532-1BRD 4354 1mg
A19532-25BRD 4354 25mg
A19532-10BRD 4354 10mg

Popular Products