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BRD-K20733377

CAT: 0013-GTR19240013-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19240013-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BRD-K20733377 is a selective Bcl-2 inhibitor that induces senolytic activity, demonstrating an IC50 of 10.7 μM against etoposide-induced senescent IMR-90 cells in vitro. It also downregulates senescence markers like p16 and p21 in aged mouse models, supporting its use in aging and senescence-related disease research.
CAS Number
452350-43-5
Field of Research
Cell Biology
Smiles
O=C (NC1=CC=C (C=C1) S (=O) (=O) NC2=NC=CC=N2) C=3C=CC (=CC3) C=4C=CC=CC4
Molecular Formula
C23H18N4O3S
Molecular Weight
430.48
Storage Conditions
-20°C
Notes
For research use only.

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