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FLI-06

CAT: 0013-GTR19171491-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19171491-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
FLI-06 is a cell-permeable small molecule inhibitor of the Notch signaling pathway, exhibiting an EC50 of 2.3 μM. It is a valuable research tool for investigating Notch-mediated processes in various cancer and developmental biology studies, applicable in both cellular and animal model systems.
CAS Number
313967-18-9
Product Name Alternative
Notch, inhibit, FLI 06, FLI06, FLI-06, Inhibitor, Gammasecretase
Field of Research
Musculoskeletal & Connective Tissue Research, Neuroscience, Protein Biochemistry, Stem Cell & Developmental Biology
Purity
>98%
Bioactivity
Notch pathway inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 10 mg/ml) .
Smiles
CC1=C (C (C2=C (CC (C) (C) CC2=O) N1) c1ccc (cc1) [N+] ([O-]) =O) C (=O) OC1CCCCC1
Molecular Formula
C25H30N2O5
Molecular Weight
438.52
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
Cyclohexyl-1,4,5,6,7,8-hexahydro-2,7,7-trimethyl-4- (4-nitrophenyl) -5-oxo-3-quinolinecarboxylate

Chemical Information

Cyclohexyl 2,7,7-trimethyl-4-(4-nitrophenyl)-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate

gamma-secretase inhibitor

CAS Number313967-18-9
PubChem CID3103157
IUPAC Namecyclohexyl 2,7,7-trimethyl-4-(4-nitrophenyl)-5-oxo-1,4,6,8-tetrahydroquinoline-3-carboxylate
Molecular FormulaC25H30N2O5
Molecular Weight438.5
XLogP4.9
Topological Polar Surface Area101
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count4
Heavy Atom Count32
Formal Charge0
Complexity852
SMILES
CC1=C(C(C2=C(N1)CC(CC2=O)(C)C)C3=CC=C(C=C3)[N+](=O)[O-])C(=O)OC4CCCCC4
InChI
InChI=1S/C25H30N2O5/c1-15-21(24(29)32-18-7-5-4-6-8-18)22(16-9-11-17(12-10-16)27(30)31)23-19(26-15)13-25(2,3)14-20(23)28/h9-12,18,22,26H,4-8,13-14H2,1-3H3
InChIKey
SWWVFYHSSOWZMF-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Cyclohexyl 2,7,7-trimethyl-4-(4-nitrophenyl)-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate
CAS: 313967-18-9
CID: 3103157
Formula: C25H30N2O5
MW: 438.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight438.5
XLogP34.9
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count4
Exact Mass438.21547206
Monoisotopic Mass438.21547206
Topological Polar Surface Area101 Ų
Heavy Atom Count32
Formal Charge0
Complexity852
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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Alternative Products

CatalogName
B3083-25FLI-06
255313-01FLI 06

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