Mepazine

CAT: 0013-GTR19174269-02Size: 1 ml x 10 mM (in DMSO)Dry Ice: NoHazardous: No

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CAT#:0013-GTR19174269-02Size:1 ml x 10 mM (in DMSO)

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Description

Mepazine (Pecazine) is a potent, selective MALT1 protease inhibitor, demonstrating IC50 values of 0.83 μM and 0.42 μM against full-length and truncated forms, respectively. It is a valuable research tool for studying NF-κB signaling, lymphocyte activation, and inducing apoptosis in various lymphoma cell lines in vitro.

CAS Number

60-89-9

Product Name Alternative

ABC-DLBCL, Apoptosis, B cell, diffuse, Inhibitor, MALT1, Mepazine, large, mucosa associated lymphoid tissue lymphoma translocation gene 1, inhibit, lymphoma, Pecazine

Field of Research

Cell Biology, Immunology & Inflammation

Purity

99.78% (May vary between batches)

Solubility

DMSO:25 mg/mL (80.53 mM)

Smiles

CN1CCCC (CN2c3ccccc3Sc3ccccc23) C1

Molecular Formula

C19H22N2S

Molecular Weight

310.46

Storage Conditions

-20°C

Notes

For research use only.

Chemical Information

Pecazine

Pecazine is a member of phenothiazines.

CAS Number	60-89-9
PubChem CID	6075
IUPAC Name	10-[(1-methylpiperidin-3-yl)methyl]phenothiazine
Molecular Formula	C19H22N2S
Molecular Weight	310.5
XLogP	5.6
Topological Polar Surface Area	31.8
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	2
Heavy Atom Count	22
Formal Charge	0
Complexity	352

SMILES

CN1CCCC(C1)CN2C3=CC=CC=C3SC4=CC=CC=C42

InChI

InChI=1S/C19H22N2S/c1-20-12-6-7-15(13-20)14-21-16-8-2-4-10-18(16)22-19-11-5-3-9-17(19)21/h2-5,8-11,15H,6-7,12-14H2,1H3

InChIKey

CBHCDHNUZWWAPP-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 60-89-9

CID: 6075

Formula: C19H22N2S

MW: 310.5

Interactive 3D Structure

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View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	310.5
XLogP3	5.6
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	2
Exact Mass	310.15036988
Monoisotopic Mass	310.15036988
Topological Polar Surface Area	31.8 Å²
Heavy Atom Count	22
Formal Charge	0
Complexity	352
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	1
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Related Products

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GTR19199961-01	Mepacrine

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T16040-01	Mepazine
HY-121282B	Mepazine (acetate)
T69634-01	Mepazine acetate
MBS5803861	Mepazine hydrochloride
HY-121282A-01	Mepazine (hydrochloride)

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Chemical Information

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