Products for Research Use Only
RegisterLogin

VU0361737

CAT: 0013-GTR19168139-02Size: 25 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19168139-02Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
VU0361737 (ML-128) is a selective positive allosteric modulator of mGlu4 with EC50 values of 240 nM for human and 110 nM for rat receptors. It shows weak activity at mGlu5 and mGlu8, is inactive at other mGlu subtypes, crosses the blood-brain barrier, and is used in Parkinson's disease research involving in vitro and in vivo experiments.
CAS Number
1161205-04-4
Product Name Alternative
Disease, inhibit, neuroprotective, ML128, ML-128, ML 128, Parkinson's, mGluR, mGluR4 (Human), mGluR4 (Rat), Metabotropic glutamate receptors, Inhibitor, VU0361737, VU-0361737, VU 0361737
Field of Research
Neuroscience
Purity
99.09% (May vary between batches)
Solubility
10% DMSO+90% Corn Oil:2 mg/mL (7.61 mM) ; DMSO:45 mg/mL (171.3 mM)
Smiles
COc1cc (NC (=O) c2ccccn2) ccc1Cl
Molecular Formula
C13H11ClN2O2
Molecular Weight
262.69
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

VU0361737
CAS Number1161205-04-4
PubChem CID44191096
IUPAC NameN-(4-chloro-3-methoxyphenyl)pyridine-2-carboxamide
Molecular FormulaC13H11ClN2O2
Molecular Weight262.69
XLogP2.6
Topological Polar Surface Area51.2
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count3
Heavy Atom Count18
Formal Charge0
Complexity288
SMILES
COC1=C(C=CC(=C1)NC(=O)C2=CC=CC=N2)Cl
InChI
InChI=1S/C13H11ClN2O2/c1-18-12-8-9(5-6-10(12)14)16-13(17)11-4-2-3-7-15-11/h2-8H,1H3,(H,16,17)
InChIKey
ARYUXFNGXHNNDM-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of VU0361737
CAS: 1161205-04-4
CID: 44191096
Formula: C13H11ClN2O2
MW: 262.69
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight262.69
XLogP32.6
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count3
Exact Mass262.0509053
Monoisotopic Mass262.0509053
Topological Polar Surface Area51.2 Ų
Heavy Atom Count18
Formal Charge0
Complexity288
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19196181-01VU0361747
GTR19231180-01VU0364739
GTR19259573-01VU0364739

Alternative Products

CatalogName
T6726-01VU0361737

Popular Products