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VU0361737

CAT: 0931-T6726-01Size: 1 mL - 10 mM (in DMSO)Dry Ice: NoHazardous: No
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CAT#:0931-T6726-01Size:1 mL - 10 mM (in DMSO)
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1161205-04-4
Target
GluR
Related Pathways
Neuroscience
Purity
0.9986
Bioactivity
VU0361737 (ML-128) is a specific positive allosteric modulator (PAM) of the mGlu4 receptor with an EC50 of 240 nM for human receptors and 110 nM for rat receptors. It exhibits weak activity at mGlu5 and mGlu8 receptors and is inactive at mGlu1, mGlu2, mGlu3, mGlu6, and mGlu7 receptors. The compound can penetrate the CNS.
Smiles
COc1cc(NC(=O)c2ccccn2)ccc1Cl
Molecular Formula
C13H11ClN2O2
Molecular Weight
262.69
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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